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Premise #1
Sperm DNA Fragmentation (SDF) negatively impacts
ART outcomes
Esteves, 17
Translating the impact of SDF to Clinical Practice
IVF/ICSI Pregnancy Outcome
• 70 studies
• 9363 IVF cycles
• 6260 ICSI cycles
• 2121 mixed IVF/ICSI
Simon et al., Best Pract Res Clin Obstet Gynaecol 2017 Esteves, 18
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