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Scenarios for in vitro gametogenesis (PubMed: in vitro spermatogenesis: > 3000 hits)
Some experiments on spermatogenesis in vitro.
Goldschmidt. PNAS 1: 220‐222 (1915)
Initiation of spermatogenesis in vitro.
Steinberger et al. Endocrinol 74: 788‐792 (1964)
In vitro differentiation of germ cells from nonobstructive azospermic patients using three‐dimensional culture in a collagen matrix.
Lee et al., Fertil Steril 87: 824‐833 (2007)
In vitro post‐meiotic germ cell development from human embryonic stem cells.
Aflatoonian et al., Hum Reprod 24: 3150‐3159 (2009)
PSCDGs of mouse multipotent adult germine stem cells can enter and progress through meiosis to form haploid germ cells in vitro.
Nolte et al., Differentiation 80:184‐94 (2010)
In vitro production of functional sperm in cultured neonatal mouse testes.
Sato et al. Nature 471: 504‐507 (2011)
New horizons for in vitro spermatogenesis?
An update on novel three‐dimensional culture systems as tools for meiotic and post‐meiotic differentiation of testicular germ cells Stukenborg et al. Mol Hum Reprod 15: 521–529, 2009
Abu Elhija M, Lunenfeld E, Schlatt S, Huleihel M. Differentiation of murine male germ cells to spermatozoa in a soft agar culture system.
Asian J Androl. 14:285-93 (2012)
Stukenborg JB, Wistuba J, Luetjens CM, Elhija MA, Huleihel M, Lunenfeld E, Gromoll J, Nieschlag E, Schlatt S. Coculture of spermatogonia with somatic cells in a novel three- dimensional soft-agar- culture-system. J Androl 29: 312-29 (2008)
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