Page 62 - PCC10

The first patients become adults....
• diagnosed with drepanocytosis
• at age 9: need for bone-marrow transplantation
• referred for testicular stem cell banking (2006)
• 2016: wants to know his “fertility status”
• semen analysis: “azoospermia”
• but after centrifugation: 5 motile sperm...
Already had treatment?
Limited numbers of spermatogonial stem cell for transplantation are to be expected if
• previous exposure to chemotherapy
• conditions with reduced spermatogonial stem cell numbers
What about spermatogonial stem cell “quality” in such cases?
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