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 Who should cryobank before gonadotoxic treatment?
    Childhood malignancies: many will remain (sub)fertile
Benign hematological disorders or systemic diseases requiring hematopoietic stem cell transplantation: many will become infertile
Patients with Klinefelter’s syndrome: experimental ? Patients with cryptorchid testes: controversial
           Who should cryobank before gonadotoxic treatment?
 >80% risk for sterility
• whole body irradiation
• conditioning for bone-marrow transplantation
• Hodgkin treated with alkylating agents
• metastatic Ewing’s sarcoma
• metastatic soft-tissue sarcoma
• testicular radiotherapy
  • •
Wallace et al. Lancet Oncol. 2005
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