Page 61 - PCC10
P. 61
Who should cryobank before gonadotoxic treatment?
Childhood malignancies: many will remain (sub)fertile
Benign hematological disorders or systemic diseases requiring hematopoietic stem cell transplantation: many will become infertile
Patients with Klinefelter’s syndrome: experimental ? Patients with cryptorchid testes: controversial
Who should cryobank before gonadotoxic treatment?
>80% risk for sterility
• whole body irradiation
• conditioning for bone-marrow transplantation
• Hodgkin treated with alkylating agents
• metastatic Ewing’s sarcoma
• metastatic soft-tissue sarcoma
• testicular radiotherapy
• •
Wallace et al. Lancet Oncol. 2005
Page 55 of 135
PRECONGRESS COURSE 10 I BARCELONA, SPAIN – 1 JULY 2018 61