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Transplant HLA and ABO Matching
Kidney Liver Heart Lung Pancreas Cornea Stem cell
HLA ABO No* Yes No Yes No Yes No Yes No* Yes No No
Yes No *HLA matching preferred but not required
HSCT: Donor Selection
• HLA compatibility essential
• ABO compatibility not required
• Siblings: best chance for identity
• 25% chance of matching any one sib
• Other family members may match pt (Haploidentical donor)
• No MRD? Search for MUD ASAP!
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