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Reconstitution in vitro of the entire cycle of the mouse female germ line Hikabe, 2016
In vitro oogenesis:
In vitro differentiation In vitro growth
in vitro maturation
Offspring from in vitro generated eggs
Reconstitution of the second cycle
of oogenesis in vitro PCC Genetics - ESHRE BCN 2018
Complete Meiosis from Embryonic Stem Cell- DerivedGermCellsInVitro. Zhou,2016
 Co-culture of PGCLCs with neonatal testicular somatic cells and sequential exposure to morphogens and sex hormones reproduced key hallmarks of meiosis, including erasure of genetic imprinting, chromosomal synapsis and recombination ,and correct nuclear DNA and chromosomal content in the resulting haploid cells
 ICSI of the resulting spermatid-like cells into oocytes produced viable and fertile offspring
PCC Genetics - ESHRE BCN 2018
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