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Blastocyst Methylome Analysis
486,428 CpG sites Methylation 450 BeadChip
9
Blastocyst Methylome Results
Blastocyst Beta Value
Diploid (Euploid)
0.21
Trisomy 7
0.21
Trisomy 11
0.20
Trisomy 15
0.20
Trisomy 21
0.20
Trisomy 22
0.20
Monosomy 7
0.20
Monosomy 11
0.20
Monosomy 15
0.20
Monosomy 21
0.20
Monosomy 22
0.21
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Comparable methylomes irrespective of chromosome constitution
Beta Value Calculation:
0 = no methylation (hypomethylation) 1 = full methylation (hypermethylation)
McCallie et al, 2016 Plos One
PRECONGRESS COURSE 08 I BARCELONA, SPAIN – 1 JULY 2018 51