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Defining Over-response
• Number of follicles / oocytes
> 30 25 > 15
Asch et al, Hum Rep 1991; 1395 Morris et al, Hum Rep 1995; 811 Steward et al, F&S 2014; 101
• Serum oestradiol concentrations 3000 – 6000 pg/ml
No consensus
Predicting Over-response
• High antral follicle count (AFC)
• Polycystic ovarian morphology (PCOM)
• High serum anti-müllerian hormone (AMH)
• Young age
• Slim build
• Previous history of OHSS
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