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Clomiphene vs Gonadotropin as First Line Treatment for PCOS
N = 302
7% cancellation rate for Gonadotropin, 3% multiple pregnancy rate vs 0% for CC
“FSH may be an appropriate first-line treatment for some women with PCOS and anovulatory infertility, particularly older patients.”
Homburg et al, Hum Reprod, 2012
SART Data: PCOS with Better Outcomes than Tubal Factor
Category
PCOS
Tubal
PCOS vs Tubal
OR (95% CI)
Mean # Oocytes
16.4
12.8
1.27, (1.25- 1.29)
Clinical Pregnancy Rate
43%
36%
1.32, (1.27- 1.38)
Live Birth Rate
35%
29%
1.30, (1.24- 1.35)
Page 102 of 196
Kalra et al, Fertil Steril 2013
PRECONGRESS COURSE 07 I BARCELONA, SPAIN – 1 JULY 2018 109