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Learning Objectives
– Endometriosis – definition and etiological concepts
– Terminology: sensitivity and specificity
– Laparoscopy: the current diagnostic standard
– Types of noninvasive tests in endometriosis diagnostics – Imaging in noninvasive diagnostics
– Biomarkers in urine
– Biomarkers in blood
– Combination of biomarkers
– microRNAs as potential biomarkers – Summary & Conclusions
Non-invasive biomarkers | Prof. Dr. Martin Götte
Endometriosis – a disease associated with pain and reduced fertility
• presence of endometrial tissue outside of the cavum uteri
• estrogen-dependent disease
• main symptoms: pelvic pain, dysmenorrhoea, dyspareunia
• about 5-10% of women may suffer from endometriosis
• 35- 50% correlation between pelvic pain and infertility in endometriosis!
Dunselman et al. 2014, Burney and Giudice 2012
Wolf et al. Gyn Endo, 2009 / Ferring
Non-invasive biomarkers | Prof. Dr. Martin Götte
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