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Peritubular myoid cells (PMCs)
‐Present from E13.5
‐ origin unconfirmed (coelomic epithelium and/or mesonephros)
Desert hedgehog
Dhh‐null mice – abnormal PMCs
Mesonephric‐derived cells – Vcam1+, and later also Smaα+ ‐ possible give rise to PMCs
McLaren 1998
Testis cord elongation
Fetal Leydig cells – activin A – Sertoli cell proliferation – testis cord elongation
Around birth ‐ prospermatogonia relocation and reproliferation
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PRECONGRESS COURSE 01 I BARCELONA, SPAIN – 1 JULY 2018 27