Page 44 - PRECONGRESS COURSE 06

Oocyte number and laboratory outcomes
• Retrospective cohort study: 2,455 women
0 – 5 Oocytes
6 – 10 Oocytes
11 – 15 Oocytes
≥ 16 Oocytes
P value
Number of cycles
381
965
726
383
Age
30 (21 – 34)
30 (20 ‐34)
29 (20 – 34)
28 (20 – 34)
<0.001
Oocytes retrieved
3.69 ± 1.35
8.03 ± 1.43
12.66 ± 1.36
18.95 ± 3.33
<0.001
Fertilisation rate
0.745 ± 0.277
0.723 ± 0.205
0.698 ± 0.191
0.640 ± 0.188
<0.001
Embryos transferable
2 (0 – 5)
5 (0 – 10)
8 (0 – 15)
9 (0 – 20)
<0.001
Ji et al., Hum Reprod 2013
Oocyte number and embryo implantation
IVF outcome in normal versus high responders
Normal responder
High responder
Number of IVF cycles
114
63
Age (years)
33.1 ± 3.8*
30.0 ± 2.8
Oestradiol on day of hCG (pg/ ml)
1410 ± 780*
3194 ± 1637
Oocytes retrieved (mean ± SD)
8.5 ± 2.8*
25.7 ± 9.6
Fertilisation rate (%)
65.5 ± 24.1
59.6 ± 25.2
Number of embryos transferred
3.7 ± 1.2*
4.1 ± 0.9
Implantation rate (%)
48/432 (11.1)*
14/258 (5.4)
Pregnancies (%)
38/114 (33.3)*
10/61 (16.4)
* Significant difference
Simon et al., Hum Reprod 1995
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