Page 31 - PRECONGRESS COURSE 06
P. 31

FSH β subunit SNP’s and Gonadotropin levels
(Tong et al., Fertil Steril, 2000)
60 50 40 30 20 10
Distribution of FSH-β polymorphisms
Gonadotropin serum levels according to FSH β SNP status
12 10 8 6 4 2 00
*
*
AA AB BB
Non carriers FSH
Homozygous carrier LH Testosterone
Controls
PCOS
Heterozygous cariers
FSHβ SNP’s and Pregnancy
(Grigorova et al. Annals Human Genetics, 2007)
Estonian Population Sample
Short Time to Pregnancy Sample
HAP 1 Homozygotes HAP1/13 Homozygotes
HAP 13 Homozygotes
Rare Homozygotes and other genotypes
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