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Natural versus artificial
1. Natural versus managed natural cycle
2. Artificial versus natural
3. Artificial versus CC
4. GnRHa + E versus CC
5. artificial versus FSH
Insufficient evidence to support the use of one intervention in preference to another.
Ghobara and Vandekerckhove, Cochrane Database Syst Rev, 2008 Groenewoud et al., Hum Reprod Update, 2013,
Groenewoud et al., Hum Reprod, 2016
Natural Cycle
Pregnancy outcome (CPR)
mNC-FET + LPS (n=1024)
304 (29.7%)
NC-FET + LPS (n=828)
330 (39.9%)
NC-FET (n=501)
235 (46.9%)
P-value
<0.001
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