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In vitro activation or natural resumption of ovarian function?
25,00% 20,00% 15,00% 10,00%
5,00% 0,00%
IVA vs spontaneous resumption of ovarian function
DELIVERY LIVEBORN Spontaneous delivery
FOLLICULAR GROWTH/ MENSES RESUMPION In vitro activation
Suzuki et al, Hum Reprod 2015 Bidet et al., JCEM 2011
Conclusions
Prognosis in poor responders is always poor
Ovarian stimulation has limited effect and only when follicles exist
Future research should focus on increasing the recruitable follicular pool
Testosterone or in vitro activation of primordial follicles appear promising
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