Page 143 - PRECONGRESS COURSE 06
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ESTHER Trial
Treatment protocol: N=1326
Gonal‐F: 150 IU
Rekovelle:
ESTHER Trial
Fixed dose based on AMH and body weight
GnRH‐antagonist (cetrorelix)
GF 31.6%
Dose decrease
Cum OP rate Fresh plus Frozen RV 30.7%
Stimday1 2 3 4 5 6 7 8 9 10 ....20
Non-inferiority for the primary endpoints:
Dose increase
Individualised dosing:
Not more oocytes in low responder range
Less oocytes in the high responder range
Not more GQ blastocysts...
Anderson, FS 2017
Page 139 of 258
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