Page 63 - PRECONGRESS COURSE 04

Conditional endometrial Cx26-deletion
Implantation site at 4.5 dpc
Control
Cx26-KO
luminal epithelium
blastocyst
Cx26
uterine epithelium
Bienek (2011)
0,025 0,02 0,015 0,01 0,005 0
**
qPCR
Cx26
d
control
Cx26-KO
liver
control
Cx26-KO
endometrium (4.5 dpc)
uterine epithelium
University Hospital Essen - Prof. Dr. Ruth Grümmer
ESHRE 2017 - Geneva
Effect of conditional endometrial Cx26-deletion
Implantation sites at 5.5 dpc
C Cx26-KO
C Cx26-KO
University Hospital Essen - Prof. Dr. Ruth Grümmer
Litter size Implantation sites at 5.5 dpc
C
normal blastocyst degenerated blastocyst
**
Cx26-KO C Cx26-KO
Bienek (2011)
ESHRE 2017 - Geneva
PRECONGRESS COURSE 04 I GENEVA, SWITZERLAND – 2 JULY 2017 63
number implantation chambers
Litter size
litter size
degenerated blastocysts (%)
Cx26/ ‐actin