Page 60 - PRECONGRESS COURSE 04

Mediators of endometrial Cx26 induction
Explantation of uteri
E2 CE IL-1 PGF2
in‐vitro culture of uteri (18 h)
Isolation of endometrium RNA
ESHRE 2017 - Geneva
Pseudopregnant rat
E2 = Estrogen
CE = Katechol estrogen IL‐1b = Interleukin‐1beta PGF2a = Prostaglandin F2alpha
University Hospital Essen - Prof. Dr. Ruth Grümmer
Mediators of endometrial Cx26 induction
nt
+ IL-1
+PGF2
nt
E2
CE IL‐1b PGF2a
= non treated
= Estrogen
= Katechol estrogen
= Interleukin‐1beta
= Prostaglandin F2alpha
Grümmer et al. (2004)
ESHRE 2017 - Geneva
C
+ E2
C + ICI + ActD
C + ICI
C + ICI
C + ICI
University Hospital Essen - Prof. Dr. Ruth Grümmer
+ CE
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