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Leukocytes and the endometrium
•Immune cells constitute considerable proportion of multicellular endometrial stroma
• 8.2% at proliferative phase (Bulmer et al., 1991)
• 40 – 45% prior to menstruation (Salamonsen and Lathbury, 2000)
• Neutrophilnumbersincreasedramatically at menses (Salamonsen and Woolley, 1999)
• 6 – 15% of stroma (Salamonsen and Lathbury, 2000)
• Macrophages present throughout cycle, but show an increase in number at menses (Poropatich et al., 1997)
Armstrong, GM, unpublished data
Cell type and impact of cycle stage:
Overview of steroid receptor expression in endometrium
Either re-draw table/ awaiting copyright reply
Henderson TA, Saunders PT, Moffett-King A, Groome NP, Critchley HO 2003
Steroid receptor expression in uterine natural killer cells. J Clin Endocrinol Metab 88:440-449 Copyright © 2003 The Endocrine Society
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