Page 91 - PRECONGRESS COURSE 03
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The ‘dark side’ of DNA damage
DNA repair genes maintain ovarian reserve
DNA damage is detrimental in embryos (no programmed induction of damage).
DNA damage and chromosome instability in embryos restrict their developmental potential.
Ovarian reserve and DNA damage
MEDULLA Activated follicles
CORTEX Primordial follicles
(Image courtesy of Claus Yding Andersen)
Page 87 of 102
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