Page 44 - PRECONGRESS COURSE 03
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The nucleus is off-centre in oocytes lacking the F-actin nucleator Formin 2 (Fmn2)
Fmn2 +/‐
Fmn2 ‐/‐
tu
F-actin DNA
Dumont Dev Biol 2007 Azoury CB 2008 Azoury Dev 2011
Formin 2 injection in Fmn2 -/- oocytes triggers nucleus movement towards the center
Fmn2 ‐/‐ + Fmn2 Fmn2 ‐/‐
Nuclear probe Timepoints every 20 min Nucleus
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