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Failure to put the nucleus in the centre correlates with poor meiotic division outcome
Microtubules
Acentriolar MTOCs
DNA
Łuksza Dev Biol 2013 Brunet & Maro Reprod 2007 Bellone Reprod 2009
Levi Hum Reprod 2013
Plan of the talk
• nucleus positioning is actively regulated in mouse oocytes • nucleus central positioning impacts gene expression
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PRECONGRESS COURSE 03 I GENEVA, SWITZERLAND – 2 JULY 2017 43