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Figure 2. Live birth rate in high and low sperm DNA fragmentation groups. ICSI = intracytoplasmic sperm injection.
A. Osman, H. Alsomait, S. Seshadri, T. El-Toukhy, Y. Khalaf
The effect of sperm DNA fragmentation on live birth rate after IVF or ICSI: a systematic review and meta-analysis
Reproductive BioMedicine Online, Volume 30, Issue 2, 2015, 120–127 http://dx.doi.org/10.1016/j.rbmo.2014.10.018
IVF only
ICSI only
Mixed
A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome
Simon et al. Asian J Androl2017;19:80-90
Conclusion:
There is sufficient evidence in the existing literature suggesting that sperm DNA damage has a negative effect on clinical pregnancy following IVF and/or ICSI treatment.
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