Page 292 - ESHRE2019

P-582 Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro
D. Richani1, K. Constance1, S. Lien1, D. Agapiou1, W. Stocker2, M. Hedger3, W. Ledger1, J. Thompson4, D. Robertson1, D. Mottershead5, K. Walton2, C. Harrison2, R. Gilchrist1
1University of New South Wales Sydney, Fertility and Research Centre- School of Women’s and Children’s Health, Sydney, Australia
2Monash University, Department of Physiology- Monash Biomedicine Discovery Institute, Clayton, Australia
3Hudson Institute of Medical Research, Centre for Reproductive Health, Clayton, Australia
4The University of Adelaide, Robinson Research Institute- Adelaide Medical School, Adelaide, Australia
5Keele University, Institute for Science and Technology in Medicine- School of Pharmacy, Newcastle- under-Lyme, United Kingdom
P-583 Relationship between diminished ovarian reserve and matrix metalloproteinase-9 (MMP9) p.Gln279Arg polymorphism
B. Petersen1,2, A. Renzi2, L.D. Vagnini2, C.G. Petersen1,2, A.L. Mauri1,2, M. Mattila1, J. Ricci1, F. Dieamant1,2, J.B.A. Oliveira1,2, R.L.R. Baruffi1,2, J.G. Franco Jr1,2
1Centre for Human Reproduction Prof. Franco Jr, Research, Ribeirão Preto, Brazil 2Paulista Center for Diagnosis Research and Training, Research, Ribeirao Preto, Brazil
P-584 Cumulus cell telomere length is associated with vitamin D3’s main catabolite 24,25-dihydroxyvitamin D3 concentration in serum and follicular fluid: An ovarian ageing explanation
E.E. Lara Molina1, J.M. Franasiak2, D. Marin3, A. Devesa Peiro4, 5, M. Florensa Bargallo6, M. Martin Salat6, X. Tao7, E. Seli8, P. Díaz Gimeno4, A. Pellicer9
1IVI RMA Global Barcelona, Egg Donation, Barcelona, Spain
2IVI RMA Global New Jersey, Chief of IVI RMA Global America, New Jersey, U.S.A. 3IVI RMA Global New Jersey, Research, New Jersey, U.S.A.
4IVI RMA Global, IVI Foundation, Valencia, Spain
5Instituto de Investigación Sanitaria La Fe, Analytic Unit, Valencia, Spain
6IVI RMA Global Barcelona, IVF Laboratory, Barcelona, Spain
7Foundation for Embryonic Competence, Research, New Jersey, U.S.A.
8IVI RMA Global, Innovation Chief, New Jersey, U.S.A.
9IVI RMA Global Roma, IVI RMA Global President, Roma, Italy
P-585 Inhibition of GnRH-mediated intracellular signaling in vitro differs according to type of antagonist
L. Casarini1, S. Sperduti1, S. Limoncella1, C. Lazzaretti1, E. Paradiso1, L. Riccetti1, J. Bertacchini1, C. Palumbo1, R. Millar2, S. Longobardi3, F. Wieser3, T. D’Hooghe3, M. Simoni1, C. Newton2
1University of Modena and Reggio Emilia, Department of Biomedical- Metabolic and Neural Sciences, Modena, Italy
2University of Pretoria, Centre for Neuroendocrinology and Department, Petoria, South Africa 3Merck KGaA, Global Medical Affairs Fertility, Darmstadt, Germany
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