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O-293 Clinical outcome of balance chromosome rearrangement carrier diagnosis in preimplantation human embryos by MicroSeq technique
C. Dehua1,2, L. Hu1,2,3, K. Luo1,2, X. Wu3, J.C. Cai3, P. Xie1,3, F. Gong1,2,3, Y. Tan1,2,3, C. Lu1,2,3, Z. Yang4, G. Lu1,2,3, G. Lin1,2,3
1Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Science- Central South University, ChangSha, China
2Reproductive and Genetic Hospital of CITIC-Xiangya, Genetic Center, ChangSha, China
3National Engineering and Research Center of Human Stem Cells, National Engineering and Research Center of Human Stem Cells, Changsha, China
4Reproductive Fertility Center- Irvine- California, Reproductive Fertility Center- Irvine- California, California, U.S.A.
O-294 Parallel analysis of copy number aneuploidies and ploidy level by NGS and SNP array on single biopsy provides accurate results and improves PGT-A applications range
V. Romanelli1, M. Fabiani1, L. Girardi1, L. Albricci2, L. Rienzi2, F.M. Ubaldi2, S. Caroselli1, D. Cimadomo2, C. Patassini1, M. Poli1, C. Rubio3, C. Simon3, A. Capalbo1
1igenomix Italia- molecular biology laboratory, Molecular Biology Laboratory, Marostica, Italy 2Clinica Valle Giulia, GENERA centers for reproductive medicine, Rome, Italy
3igenomix Valencia - molecular biology laboratory, Molecular Biology Laboratory, Valencia, Spain
O-295 Accuracy of mosaicism calling in PGT-A may be affected by cell numbers in biopsy specimens
J. Wei1, C. Zhang1, X. Qin1, C.J. Davidson2, A. Harris3, Z. Rosenwaks1, K. Xu1
1Weill Cornell Medical College, Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York, U.S.A.
2Thermo Fisher Scientific, research and development, South San Francisco, U.S.A. 3Thermo Fisher Scientific, research and development, Carlsbad, U.S.A.
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