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Inconsistency (heterogeneity)
• how consistent are the results of all the studies?
• consider statistical measures (I2), clinical interpretation
• has heterogeneity been adequately Forest plot A explained?
I2 =0%
Forest plot B
I2=87.2%
Inconsistency (heterogeneity)
intervals don’t overlap and
GRADE → important
Forest plot B
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PRECONGRESS COURSE 17 I VIENNA, AUSTRIA – 23 JUNE 2019 79