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How fibroids impair infertility
• Involving alteration of local anatomical location
• Involvingfunctionalchangesofthemyometrium
• Endocrine and paracrine molecular mechanisms.
• Impaired gamete transport, reduced ability for embryo implantation and creation of a hostile environement.
Zepiridis et al., 2015
and endometrium.
In 2001, Pritts et al. performed a systematic review of controlled studies. They failed to demonstrate any effect of intramural fibroids on fertility outcomes.
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