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Germline DMRs in hTS
100 80 60 40 20
Primary CT
hTS
100 80 60 40 20 00
Placenta‐specific
Placenta‐specific
Maternal Paternal
19
Ectopic grafting of hTS
Subcutaneous injection
hTS
SDC1
ST marker
NOD/scid HLA‐G
EVT marker
Okae H et al. Cell Stem Cell. 2018
KRT7
20
86
PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 89
TSCT #1 TSblast #1
KvDMR1 ZNF597 H19 AIM1 KLHL1 MIR512‐1cluster THAP3 TMEM17 ZC3H12C ZFAT KLHDC10 PCK2
KvDMR1 ZNF597 H19 AIM1 KLHL1 MIR512‐1cluster THAP3 TMEM17 ZC3H12C ZFAT KLHDC10 PCK2