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hTS
NRG1 ↑ Matrigel TGFβ ↓
HLA‐G
EVT
day4 day8
Epithelial‐Mesenchymal Transition
HLA‐G Merge
Differentiation of hTS into EVT
day2
Hoechst
NRG:Neuregulin‐1(Fock et al.2015)
13
Transcriptome profiling of hTS
EVT Primary
ST Primary
Non‐trophoblast
CT derived hTS (TSCT)
Blastocyst derived hTS
(TSBlast) 14
hTS #1‐EVT hTS #2‐EVT
hTS #3‐EVT hTS #4‐EVT
hTS
hTS #1 hTS #2
hTS #3 hTS #4
hTS
CT Primary
hTS #1‐ST hTS #2‐ST
hTS #3‐ST hTS #4‐ST
hTS
86
83
hTS #1‐EVT hTS #2‐EVT hTSC#s3-#E3V‐TEVT hTSC#s4-#E4V‐TEVT
hTS #1 hTS #2 hTSC#s3 #3 hTSC#s4 #4
hTS #1‐ST hTS #2‐ST hTSC#s3#-S3T‐ST hTTSS#C4#s4-S#-ST4T‐ST
