Page 137 - ESHRE2019

Global hiPSC bank
PCC Stem Cells - ESHRE Vienna 2019
Approximately 150 consecutive blood group compatible donors, 100 consecutive blood group O donors, or ten highly selected homozygous donors could provide the maximum practical benefit for HLA matching. The findings from these simulations have practical, political, and ethical implications for the establishment of hES-cell banks.
Nakasuki et al, 2008
Bank of pluripotent stem cell lines with HLA-A, HLA-B and HLA-DRhaplotypesisfeasible and would covera
large majority of the Japanese population.
Furthermore, our estimates suggest HLA homozygote donors could be readily identified from the HLA databases already used in bone marrow donor banks or cord blood banks.
PCC Stem Cells - ESHRE Vienna 2019
132
PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 135