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Are HBsAg & Anti‐HBc suitable tests?
ACUTE INFECTION
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Testing for anti‐HBc before ART questionable
 Shows evidence of ‘occult’ Hep B infection
 Rationale behind testing based on evidence from blood transfusions
not ART
> 200,00 blood donors
67 donors identified as having occult HBV infection (0.03%) 45 of these followed‐up
One case of potential post transfusion transmission
 HBsAg: reasonable screening test
 Anti-HBc: questionable screening test
HFEA/ EUTCD advise screening for HBV viral load if Anti-HBc positive
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PRECONGRESS COURSE 12 I VIENNA, AUSTRIA – 23 JUNE 2019 81