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 Key Questions – PICO Questions
• Should [intervention] vs. [comparison] be used for [health problem] / [population]?
• Should [intervention] vs. [comparison] be used to diagnose [target condition] in [health problem and/or population]?
                             PICOcomponents
• Patients
• Interventions • Comparison • Outcome
Search terms Inclusion/exclusion criteria
                  Methodology
• Literaturereviews
• Expert group consultations
• Other guideline reviews (associate specialties) – ESHRE
– International/ Society
– European Expert views
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