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New french recommandations (INCA) in 2017: Under colposcopy control to limit excision size No systematic second procedure if no margin HPV status more important in follow up
1997-2005 (552 678 singletons, 19049 preterm, 8 180 subsequent to Loop electrosurgical excision procedure): 6% increase in risk of pretem delivery per each additional millimeter of tissue excised (OR: 1,06 95% [1,03-1,09])
LEEP: RRX2 / no LEEP
2or+LEEP:RRX4 /noLEEP
9
IB1, <2cm, no LVSI, N-:
Radical trachelectomy
De-escalation ? (on going studies)
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