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The embryo is chromosomally mosaic
Vanneste et al., Nature Medicine, 2009
Analysis of genome of all blastomeres at different stages of development
Day 0 Day 1 Embryonic stage zygot
e
Day 2
Day 3
Day 4 Day 5 Day 6 Day 7 morula blastocyst
Days after fertilization
2‐cell
4‐cell
8‐cell
Euploid cell
Cell with acquired monosomy
Cell with acquired trisomy
Euploid cell in inner cell mass (ICM) Euploid cell in trophectoderm (TE) Missegregation error
Fernandez et al., unpublished
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