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Prospective study results
No. (%) No. of couples 2295 Average maternal age 37.6
Analysed blastocysts 8830
- Euploid
-Uniformly aneuploid
- Mosaic diploid/aneuploid
3106(35%) 4802(54%)
922(10%)
No. of mosaic embryos transferred 206
No. of mosaic embryos transfer 205 No. Of euploid embryos transferred 520 No. Of euploid embryos transfer 519
Update from Spinella et al. Fertil Steril 2018;109:77-83
Clinical outcome after transfer of mosaic embryos 8830 blastocysts analyzed
922 (10%) diploid/aneuploid mosaic embryos detected
The transfer of 206 mosaic embryos was made available to a consecutive non-selected
series of 205 women for whom IVF/PGT has resulted in no euploid embryos
109 (49.7%) pregnancies (+βHCG) ensued, of which 64 (31.1%) resulted in the birth of a
healthy newborn
Prenatal diagnosis performed by CVS (51%) or Amniotic Fluid (49%) resulted in normal karyotype
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