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Genital tract microbiota impact reproductive outcomes qPCR classification of vaginal microbiota (VM) and reproductive outcome of IVF patients1 Abnormal vaginal microbiota may be associated with poor reproductive outcomes1 IVF, in vitro fertilization; LDM, Lactobacillus‐dominated microbiota non‐LDM, non‐Lactobacillus‐dominated microbiota; OTU, operational taxonomic unit Endometrial microbiota is related to pregnancy outcomes for IVF patients2 Presence of NLDM in a receptive endometrium is associated with significant decreases in implantation, pregnancy, ongoing pregnancy and live birth rates2 Normal VM Abnormal VM (N = 62) (N = 22) Biochemical pregnancy 32 (52%) 6 (27%) Clinical pregnancy 27 (44%) 2 (9%) Lactobacillus Non‐ OTUs (N = 17) Lactobacillus OTUs (N = 15) Live birth rate/transfer 10/17 1/15 (58.8%) (6.7%) Difference P=0.002 1. Haahr T, et al. Hum Reprod. 2016;31:795–803; AARHUS UNIVERSITY DEPARTMENT OF CLINICAL MEDICINE 2. Moreno I, et al. Am J Obstet Gynecol. 2016;215:684–703 PETER HUMAIDAN PETER.HUMAIDAN@MIDT.RM.DK PROFESSOR Possible impact of microbiota during early implantation Benner M et al., HRU, 2018 AARHUS PETER HUMAIDAN UNIVERSITY PETER.HUMAIDAN@MIDT.RM.DK PROFESSOR DEPARTMENT OF CLINICAL MEDICINE 62 59