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Live Birth in High DFI Patients by Intervention P=0.02 43.7% NS 24.9% None 32.7% NS 24.0% IMSI PICSI Testi-ICSI Esteves, 21 • Retrospective cohort 1924 patients • General IVF-ICSI population • Elevated DFI defined >29% • All blastocyst Transfer Andrology 2016 Sperm DNA damage and clinical pregnancy meta‐analysis Simon L et al., 2017 52 PRECONGRESS COURSE 09 I VIENNA, AUSTRIA – 23 JUNE 2019 55