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Age related decline in euploidy rates of blastocysts Analysis of 1,220 trophectoderm biopsies from 436 patients Esteves et al., ESHRE 2018; submitted Courtesy of Ubaldi & Rienzi (GENERA; 2012‐ 2013) Esteves, 11 1.2 1.9 Blastocyst euploidy rate declines every year 1220 trophectoderm biopsies Analysis of 1,220 trophectoderm biopsies from 436 patients undergoing ICSI and PGT‐A with NGS Geometric mean of the yearly variation: 13.6% 8.2 17.9 15.7 22.4 20.2 2.6 Esteves et al., ESHRE 2018; O‐007 6.7 4.4 5.5 3.4 13.6 11.6 9.8 26.6 24.5 *The % decrease in blastocyst euploidy probability from year (t) to year (t+1) was defined as the ratio p(t+1)/p(t) x 100 50 47