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• Multicenter three arm, parallel group, randomised controlled non‐ inferiority trial involving 17 centres in the Netherlands • Couples with at least 12 months of unexplained or mild male subfertility, with the female partner between 18 and 38 years, an unfavourable prognosis for natural conception. 201 3 cycles of IVF‐ SET 104 (52%) live birth 6% Multiple birth 602 couples 194 6 cycles of IVF‐ MNC 83 (43%) live birth 5% Multiple birth 207 6 cycles of IUI‐COS 97 (47%) live birth 7% Multiple birth Mean costs per couple. R.I. Tjon-Kon-Fat et al. Hum. Reprod. 2015;humrep.dev193 © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com 120 PRECONGRESS COURSE 09 I VIENNA, AUSTRIA – 23 JUNE 2019 123