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“Are we overusing IVF?” Kamphuis et al, BMJ 2014 No. (%) IVF cycles in years 2000 2011 (HFEA) Unexplained subfertility 6204 (18%) 19552 (32%) • IVFtreatmenteffectiveinsubfertility>4years; • IVF no more effective than less invasive alternatives in subfertility <2.5 years; • IVF effectiveness unknown for subfertility 2.5‐4 years IVF for unexplained infertility. Pandian, Bhattacharya, Vale & Templeton IVF for unexplained infertility. Cochrane Database, 2005 • No difference in live‐birth rates between IVF and IUI either with or without ovarian stimulation. Updated in 2012 • No difference in live birth rates, IVF versus IUI + COS ‐ OR 1.09 (0.74‐1.59) 112 PRECONGRESS COURSE 09 I VIENNA, AUSTRIA – 23 JUNE 2019 115