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Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility Diamond, Legro et al, NEJM, 373, 1230, 2015 • RCT,n=900unexplainedinfertility Live birth Gonadotrophins Clomiphene Letrozole 32.2% 23.3% 18.7% Unexplained Infertility IUI or IVF? • Efficiency • Multiple pregnancy rate • Complications • Drop outs • Cost efficiency Using RCT’s & live birth rates 108 PRECONGRESS COURSE 09 I VIENNA, AUSTRIA – 23 JUNE 2019 111