Page 22 - ESHRE2019

Follicle depletion after freeze/graft
Inhibin A in ovarian vein
Primordial follicle number after grafting fresh or frozen- thawed cortical tissue from sheep ovaries to SCID
mice
Graft type (group no.)
1)Control 2)Fresh
3) Frozen‐ thawed
Primordial follicles
No.• •sem %ofcontrol 192• •47
68• •11 35
54• •12 28
3000
2500
2000
1500
1000
500 0
Control
Transplant
Thus most follicles are lost during engraftment, not freezing
MRC Centre for Reproductive Health at the University of Edinburgh
Gosden RG et al 1994 Human Reprod Baird DT et al Endocrinology. 1999;140(1):462-471
Range of surgical techniques
MRC Centre for Reproductive Health at the University of Edinburgh
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