Page 128 - ESHRE2019

Oocyte In Vitro Maturation
 In Vitro Maturation (IVM):
Maturation of the retrieved immature occytes
in the special culture environment
 Clinical applications in FP in cancer patients:
‐ Emergency oocyte retrieval due to malignancies
‐ Oocyte retrieval from ovarian tissue before
cryopreservation
52
Oocyte In Vitro Maturation
Clinical Protocol
 Unstimulated IVM cycles without hCG priming (Cha et al., 2000)
 FSH priming IVM cycles (75‐150 IU/day for 3 days. Star at day 3)
(Lin et al., 2003; Mikkelsen and Lindenberg 2001)
 hCG priming IVM cycles assoiated or not with mild ovarian stimulation
(10.000 IU ‐ 20.000 IU when the follicle with the largest diameter reaches 10‐12 mm)
(Chian et al., 2000; Son et al., 2008)
53
126
123