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Combination of the non‐invasive tests for the diagnosis of endometriosis
Pelvic endometriosis
Marker 1
IL‐6 Serum
VDBP Urine
Length of Menses
Marker 2
PGP 9.5 Endometrium
CA‐125 Serum
CA‐125 Serum
Marker 3
Leucocytes Endometrium
Sensitivity
1.00
0.74
0.61
95% CI
0.91, 1.00
0.60, 0.84
0.54, 0.69
Specificity
0.93
0.97
0.95
95% CI
0.80, 0.98
0.86, 1.00
0.91, 0.98
Nisenblat et al., Cochrane Database Syst Rev 2016
Combination of the non‐invasive tests for the diagnosis of endometriosis
None of the biomarkers evaluated in this review could be evaluated in a meaningful way and there was insufficient or poor‐quality evidence.
Laparoscopy remains the gold standard for the diagnosis of endometriosis and using any non‐invasive tests should only be undertaken in a research setting.
Nisenblat et al., Cochrane Database Syst Rev 2016
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