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The eutopic endometrium from patients with endometriosis is different from that of healthy controls
These differences in gene expression can be used for diagnosis of endometriosis
Endometrial RNA as biomarker for endometriosis
• Eutopic endometrium = ‘semi-invasive’
• RNA profiles versus single molecules (RNA – proteins – cytokins –etc.)
• Confounders
o Menstrual cycle
o Inflammatory conditions (hydrosalpinx,...)
o Estrogen dependent diseases (adenomyosis, leiomyomata, EM- polyps,...) o Etc.
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PRECONGRESS COURSE 03 I VIENNA, AUSTRIA – 23 JUNE 2019 107