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  Evolution of non‐invasive methods for embryo assessment
   Single‐point morphological assessment
Continuous embryo monitoring
 Automated image analysis platforms
        19971
Manual algorithms
20112     2018
3
D3 culture
Blastocyst culture
    1Payne et al. Hum Reprod. 1997;12:532–541. 2Meseguer et al. Hum Reprod. 2011;26:2658–2671.
              Abnormal Cleavages; Direct Cleavages and blastulation
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