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Association is not causation
• “As the association between DNA fragmentation and pregnancy outcome is well established the analysis can be fully implemented as a diagnostic tool in the fertility clinics”
• Association
• Arelationwasfoundbetween2variables • Istherelationshipduetootherfactors?
• Controllingforconfoundershelps
• Causation
• Achangeinthevariableunderstudydirectlycausedachangein the outcome
Question 2
Can sperm DNA damage tests predict pregnancy after assisted reproductive techniques?
a) Is there a difference between the tests used b) Is there a difference between IVF and ICSI
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PRECONGRESS COURSE 01 I VIENNA, AUSTRIA – 23 JUNE 2019 85