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Is there a moral obligation for preconception carrier screening in general?
 Very controversial claim!
 Prevention paradigm vs autonomy paradigm
 Concerns related to eugenics, disability critique etc.
 Are there any morally significant differences between natural conception and donor conception that would explain why there would be a moral obligation to screen donors?
 Donors have more offspring  Donors are replaceable
 Product liability applies
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Donors have more offspring and thus the risk is larger
Is this a valid argument?
No, in the sense that sperm donation does not increase the prevalence of genetic diseases. No, in the sense that the risk for the individual recipient is not increased.
Yes, when looking at cost‐effectiveness: screening a handful of donors covers hundreds of (virtual) children.
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