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Improved concordance rates for aneuploidy detection in spent culture media compared to trophectoderm biopsies: a step forward towards non-invasive preimplantation genetic testing (niPGT-A)
C. Rubio LLuesa1, L. Rienzi2, L. Navarro-Sánchez1, D. Cimadomo2, C.M. García-Pascual1, L. Albricci2, L. Martínez-Merino1, A. Capalbo3, F. Ubaldi2, C. Simón4
1IGENOMIX, PGS Research, Paterna Valencia, Spain
2GENERA Centres for Reproductive Medicine, Reproductive Medicine, Rome, Italy
3IGENOMIX, Laboratory Director, Rome, Italy
4University of Valencia- INCLIVA- Igenomix, Obstetrics and Gynecology, Paterna Valencia, Spain
Concordance rates among multiple trophectoderm samples and ICM remain high proving the efficacy of NGS for preimplantation genetic screening
R. Anderson1, J.B. Whitney2, C.M. Rios3, A.E. Jones4, A. Harutunian3, M.C. Schiewe2
1The Southern California Center for Reproductive Medicine, ART Clinic, Newport Beach, U.S.A. 2Ovation Fertility, ART Lab, Newport Beach CA, U.S.A.
3Ovation Fertility, Genetics, Las Vegas NV, U.S.A.
4Ovation Fertility, Genetics, Nashville TN, U.S.A.
What is the genetic significance of blastomeres excluded from the formation of a morphologically normal blastocyst?
C. Pirkevi Cetinkaya1, M.A. Tufekci1, Y. Kumtepe Colakoglu1, M. Cetinkaya1, S. Kahraman1
1Istanbul Memorial Hospital, Assisted Reproductive Technologies and Reproductive Genetics Center, Istanbul, Turkey
Human in vitro post-implantation culture models reveal the depletion of aneuploid cells in chromosomally mosaic embryos 12 days post fertilisation
M. Popovic1, A. Dheedene2, L. Dhaenens1, J. Taelman1, P. De Sutter1, S.M. Chuva De Sousa Lopes1,3, B. Menten2, B. Heindryckx1
1Ghent University Hospital, Ghent-Fertility and Stem cell Team G-FaST- Department for Reproductive Medicine, Ghent, Belgium
2Ghent University Hospital, Center for Medical Genetics, Ghent, Belgium
3Leiden University Medical Center, Department of Anatomy and Embryology, Leiden, The Netherlands
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FINAL PROGRAMME I BARCELONA, SPAIN – 1 TO 4 JULY 2018 171
SCIENTIFIC PROGRAMME WEDNESDAY, 4 JULY