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Hazard ratio for menopause < 40 yrs in treatment of HL
ABVD with pelvic RT ABVD Alkylating, pelvic RT Alkylating, no pelvic RT Pelvic RT No alkylating, no pelvic RT
All adjusted for age
0 10 20 30 40
Swerdlow AJ et al 2014, J Natl Cancer Inst
overall n=2127: but data from only 50%
Gonadotoxicity of treatment for adult HL
20 15 10
5
ABVD BEACOPP
Anderson RA et al unpublished
0
chemo
EOT 1
Years after chemo
Pre 2 cycles
2 3
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PRECONGRESS COURSE 16 I BARCELONA, SPAIN – 1 JULY 2018 19
AMH (pmol/L)
